SonRTM

World's only contractility sensor for automatic CRT optimization

Healthcare Professionals Cardiac Rhythm Management SonR™

THE RESPOND CRT SYSTEM

SonRTM CRT-D + SonRtipTM Atrial Lead

The Respond CRT system is a unique combination of a cardiac contractility sensor with an advanced optimization algorithm.

  • Continuous measurement of the contractility of the heart allowing for automatic optimization of AV and VV intervals.
  • Weekly optimization at rest and exercise.
  • 35% risk reduction in HF hospitalization.1
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INFOGRAPHIES2

SONR SENSOR

The SonR sensor consists of a micro-accelerometer embedded in the tip of the SonRtip atrial lead.

SonR measures the vibrations generated by the myocardium during cardiac contractions, which are correlated to LV dP/dt max.2,3,4


SONR AV & VV OPTIMIZATION ALGORITHM

SonR sensor continuously measures the contractility of the heart allowing for automatic optimization of AV and VV intervals. Optimization is performed on a weekly basis both at rest and during exercise.

This allows for cardiac resynchronization therapy to be continuously adapted to the individual needs of each patient.


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RESPOND-CRTTM TRIAL1

SonRTM optimization is as effective as echo-guided optimization.

The RESPOND-CRT trial successfully met its primary endpoint demonstrating that automatic AV & VV optimization with SonR technology is safe and as effective as best practice AV and VV optimization using echocardiography.
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75% of clinical responders in the SonR group versus 70% in the control group (p<0.001) at 12 months.

SonRtip proven to be safe.

The rate of successful implantation of the SonRtip was 99.8% and the freedom from acute and chronic complications was 98.5% and 99.8%, respectively. Complications were very rare, with a 1% right atrial lead dislodgement rate.

35% risk reduction in heart failure hospitalization.

The RESPOND-CRT landmark trial revealed that sensor-based CRT optimization with SonR is associated with a 35% reduced risk in heart failure hospitalization.

Visit the RESPOND-CRT website for more information

This feature is not available for sale or distribution in the USA. For further information on product availability, please contact your local representative.

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Graph SONR 1

REFERENCES

  1. Brugada, J, et al. Contractility sensor-guided optimization of cardiac resynchronization therapy: results from the RESPOND-CRT trial. Euro Heart J 2016;38:730–38.
  2. Rickards AF, Bombardini T, Corbucci G, Plicchi G. An implantable intracardiac accelerometer for monitoring myocardial contractility. The Multicenter PEA Study Group. Pacing Clin Electrophysiol. 1996 Dec;19(12 Pt 1):2066-71.
  3. Bongiorni MG, Soldati E, Arena G, Quirino G, Vernazza F., Bernascoi B, Garberoglio B. Is local myocardial contractility related to endocardial acceleration signals detected by a transvenous pacing lead? Pacing Clin Electrophysiol. 1996 Nov;19:1682-88.
  4. Bordachar P, Garrigue S, Ritter P, Ploux S, Labrousse L, Casset C, Haissaguerre M, Dos Santos P. Contributions of a hemodynamic sensor embedded in an atrial lead in a porcine model. J Cardiovasc Electrophysiol. 2011 May;22(5):579-83.